Since the question is in the student section, I will respond as if you were a student...
If the quantity of heat released due to reaction were small compared to the condensation duty, I would ignore it as being covered by my equipment design safety factor. Otherwise, account for the duty in another way. For example, if the reaction duty were 25% of the condensation duty, I would consider increasing the feed flow by 25% before calculating the exchanger design in order to be conservative. You could instead model increased feed superheat by adding the duty to the original feed stream in the model, or a combination of the two methods. An even fancier way would be to adjust the heat of vaporization of the condensing stream so that the extra duty is automatically included. Check whether the reaction affects other important heat transfer parameters like surface tension or viscosity.