nivedita12:
I have designed, built, and operated adsorption systems for many gases destined for subsequent liquefaction. This has involved a product moisture in some cases as low as less than -100 oF.
I agree with Bobby's experience. I never used more than 3 towers in any one system. After careful study and field experience, I found that more towers only complicated the process and increased the risk of process upsets due to multiplicity of the only moving parts involved in the process - the critical block valves that separate the drying towers from the regenerating towers. Additionally, I found that more towers cost more. Unlike what you state, I always found that the two-tower system was a lot less expensive to operate as well. I do not agree with your statement that more towers mean less regeneration requirements. Theoretically, the amount of adsorbent (and regeneration needs) is the same for a given gas capacity regardless of number of towers. In fact, in the real application, you have less heat efficiency because you have to heat and cool more vessel parts and components in more than the 2-tower design.
There is an advantage to more than 2 towers in an adsorption drying system, but it isn't what you state. Don't forget: a system supplier, if left to his/her own wishes, will always try to sell you the most expensive system.
Bobby's stress on process reliability is a very important point. And in that respect, the basic 2-tower adsorption design is not only the simplest, but inherently the most reliable. I highly recommend that you give particularly detailed attention and importance to the design, make, operating history, and reliability of the block valves and their actuators. These items, together with the required instrumentation and programming, will determine the success of the process more than any other items.