I didn't hear of velocity being a constraint in orifice sizing. They are designed for whatever the required flow might be, and the resulting fluid velocity will be determined by the specified flow and available pressure differential. That is all.
Noise and vibration are important issues. Depending on the total flowrate and pressure drop across the orifice, you might end up with significant noise and vibrations, which further may require from you to consider sequential pressure letdown (i.e. via multiple orifices in series).
Depending on the erosion potential of a fluid, some other elements of orifice design should also be carefully evaluated. For streams carrying significant amount of suspended solids, you should try to avoid using square-edge orifices because of tendency of the fluid to erode edges of the orifice over time. This also depends on what levels of accuracy you need in this particular application.
Remember that orifices are sized for a single set of process conditions. Anytime there is a change in upstream or downstream pressure, the orifice will pass a different amount of fluid. You need to keep this in mind for future operational requirements. Perhaps it is worthwhile considering a spool piece of reduced size equipped with a butterfly valve, to allow for low modulation for any set of operating conditions in future. Of course, this applies only if you require control of the branch flow - I do not know the details of your application.